ATRA-MeBS PROTAC

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ATRA-MeBS PROTAC is a cIAP-based PROTAC consisting of an all-trans retinoic acid and a methyl bestatin. ATRA is an endogenous ligand of retinoic acid receptors (RARs), which can recruit intracellular retinoic acid-binding proteins (CRABP-I and CRABP-II). MeBS can directly and selectively bind to the BIR3 domain of cIAP1, the RING domain of which promotes auto-ubiquitination.

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Molecular Formula C44H64N4O10
Molecular Weight 809

ATRA-MeBS PROTAC

Synonyms (2E,4E,6E,8E)-9-((E)-3-((((14S,17S,18R)-18-amino-17-hydroxy-14-isobutyl-2,13,16-trioxo-19-phenyl-6,9,12-trioxa-3,15-diazanonadecyl)oxy)imino)-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Shelf Life 2 years

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
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