PEG3-O-CH2COOH

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PEG3-O-CH2COOH is a PROTAC linker can be used in the synthesis of a series of SNIPER(ER)s. SNIPER(ER)s contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. SNIPER(ER)s induce polyubiquitylation and proteasomal degradation of the target proteins in the cells.

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Molecular Formula C8H16O6
Molecular Weight 208.21

PEG3-O-CH2COOH

Synonyms PEG3-O-CH2COOH; PROTAC Linker 8; HO-PEG3-CH2COOH; 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]acetic acid
Solubility 10 mM in DMSO
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere
InChI Key NUAYEVLSVMOUPE-UHFFFAOYSA-N
InChI InChI=1S/C8H16O6/c9-1-2-12-3-4-13-5-6-14-7-8(10)11/h9H,1-7H2,(H,10,11)
Canonical SMILES C(COCCOCCOCC(=O)O)O

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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