PROTAC ERα Degrader-2 - CAS 1351169-29-3


PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs).

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Molecular Formula C42H61N5O8
Molecular Weight 763.96

PROTAC ERα Degrader-2

Synonyms PROTAC ERα Degrader 2
Solubility DMSO : 200 mg/mL (ultrasonic)
Storage -20°C, stored under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Shipping Room temperature in continental US; may vary elsewhere
Canonical SMILES C[C@@]12[C@](CC/C2=N\OCC(NCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)=O)=O)([H])[C@@]4([H])[C@](C5=CC=C(O)C=C5CC4)([H])CC1

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