BTK (Bruton tyrosine kinase)

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Bruton tyrosine kinase (BTK), is a 77 kDa protein containing 659 amino acids, which can be divided into five different functional domains: Pleckstrin homologous (PH) domain is located near the N-terminal, followed by Tec homologous (TH), Src homology 3 (SH3), SH2 and SH1 or tyrosine kinase (TK) domain. BTK was initially found to be a key mediator of B cell receptor signals during acquired immune development and function. More and more evidence shows that BTK plays multiple roles in monocytes of the innate immune system, especially in dendritic cells and macrophages, and plays an important role in the proliferation and survival of leukemic cells in many B-cell malignant tumors.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-800374Recombinant Rat BTK protein, GST-tagged, ActiveInsect cellsRatGST
BP-800375Recombinant Human BTK protein, His & GST-taggedE. coliHumanHis & GST
BP-800376Recombinant Rat BTK protein, His & GST-taggedE. coliRatHis & GST
BP-800377Recombinant Human BTK, His-tagged, ActiveSf9 insect cells using baculovirus
BP-800378Recombinant Human BTK proteinInsect cellsHuman
BP-800379Recombinant Human BTK Protein, MYC/DDK-taggedHEK293HumanMYC/DDK
BP-800380Recombinant Human BTK Protein, GST-taggedWheat GermHumanGST
BP-800381Recombinant Human BTK protein, Flag-tagged, BiotinylatedInsect cellHumanFlag
BP-800382Recombinant Human BTK, His taggedBaculovirus-Insect cellsHumanHis
BP-800383Recombinant Human BTK Protein, His-taggedInsect cellsHumanHis
BP-800384Recombinant Human BTKMammalian CellsHumanHis
BP-800385Recombinant Human BTK, GST-taggedSf9 insect cells using baculovirus.
BP-800386Recombinant Chicken BTKMammalian CellsChickenHis
BP-800387Recombinant Human Bruton Agammaglobulinemia Tyrosine Kinase, His-taggedHuman

* PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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