CHMP2A (Charged multivesicular body protein 2a)

* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

CHMP2A (Charged multivesicular body protein 2a) is a protein that in humans is encoded by the CHMP2A gene. CHMP2A belongs to chromatin modified protein / charged polyvesicular protein. Possible core components of endosome sorting required for transport complex III (ESCRT-III), which involves the formation of polycystic (MVB) and the sorting of endosomal cargo proteins into MVB. MVB contains intracavitary vesicles (ILV), intracavitary vesicles are produced by invagination and incision of the endosome limiting membrane, and most of them are transmitted to lysosomes, resulting in the degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Diseases associated with CHMP2A include viral gastritis and breast cancer.

* PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.