HMGN1 (high mobility group nucleosome binding domain 1)


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HMGN1 (high mobility group nucleosome binding domain 1), also known as HMG14, is a ubiquitous vertebrate nuclear protein, which can specifically bind to nucleosome core granules (a component of chromatin fibers). The expression of HMGN1 is closely related to cell differentiation. HMGN1 is ubiquitous and highly expressed in all embryonic tissues. During mouse embryogenesis, the expression is down-regulated throughout the embryo, except for active differentiation in stereotyped but continuously renewed cell types. The expression of HMGN1 is also down-regulated during myogenesis, erythropoiesis and osteogenesis. Overexpression of HMGN1 inhibits myotube formation in C2C12 myoblasts and chondrocyte differentiation in primary limb bud mesenchymal cells, suggesting its role in blocking cell differentiation. Diseases associated with HMGN1 include cocaine syndrome and Down syndrome.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-801231Recombinant Human HMGN1, GST-taggedE.coliHumanGST
BP-801232Recombinant Mouse HMGN1 protein, His-taggedE. coliMouseHis
BP-801233Recombinant Human HMGN1, His-taggedE.coli.
BP-801234Recombinant Human HMGN1Wheat germ
BP-801235Recombinant Human HMGN1, His-taggedE. coli
BP-801236Recombinant Human HMGN1 Protein, GST-taggedWheat GermHumanGST
BP-801237Recombinant Chicken HMGN1Mammalian CellsChickenHis
BP-801238Recombinant Mouse HMGN1 ProteinMammalian CellsMouseHis

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