IFNAR2 (Interferon alpha and beta receptor subunit 2)

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The IFNAR2 (Interferon alpha and beta receptor subunit 2) protein encoded by this gene is a type I membrane protein that forms one of the two chains of interferon α and β receptors. The binding and activation of receptors stimulate Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. In addition, the IFNAR2 cytoplasmic domain plays a role in connecting STAT4 to IFNAR and becomes a preassembled complex that can promote cytokine-driven STAT4 activation. In humans, the only heterodimer receptor complex composed of IFNAR1 and IFNAR2 mediates all cellular responses triggered by type I IFN. Studies have shown that IFNAR2 is necessary for anti-influenza immunity and can change the susceptibility to superinfection of post-influenza bacteria.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-801261Recombinant Human IFNAR2 protein, His & T7-taggedE. coliHumanHis & T7
BP-801262Recombinant Cynomolgus IFNAR2 Protein, His-taggedHEK293CynomolgusHis
BP-801263Recombinant Human IFNAR2, GST-taggedE.coliHumanGST
BP-801264Recombinant Human IFNAR2, His-taggedHEK293HumanHis
BP-801265Recombinant Human IFNAR2, Fc-taggedHEK293HumanFc
BP-801266Recombinant Human IFNAR2 Protein, Fc-taggedHEK293HumanFc
BP-801267Recombinant Human IFNAR2, Fc ChimeraHuman 293 cells
BP-801268Recombinant Human IFNAR2, His-tagged
BP-801269Recombinant Human IFNAR2, His taggedHuman CellsHumanHis
BP-801270Recombinant Chicken IFNAR2Mammalian CellsChickenHis
BP-801271Recombinant Mouse IIFNAR2, Fc ChimeraNSO cellsMouseFc Chimera
BP-801272Recombinant Human Interferon(alpha, beta and omega) Receptor 2, Fc-taggedHuman CellsHumanFc
BP-801273Recombinant Mouse IFNAR2 ProteinMammalian CellsMouseHis

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