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IFNAR2 (Interferon alpha and beta receptor subunit 2)

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* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

The IFNAR2 (Interferon alpha and beta receptor subunit 2) protein encoded by this gene is a type I membrane protein that forms one of the two chains of interferon α and β receptors. The binding and activation of receptors stimulate Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. In addition, the IFNAR2 cytoplasmic domain plays a role in connecting STAT4 to IFNAR and becomes a preassembled complex that can promote cytokine-driven STAT4 activation. In humans, the only heterodimer receptor complex composed of IFNAR1 and IFNAR2 mediates all cellular responses triggered by type I IFN. Studies have shown that IFNAR2 is necessary for anti-influenza immunity and can change the susceptibility to superinfection of post-influenza bacteria.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-801261Recombinant Human IFNAR2 protein, His & T7-taggedE. coliHumanHis & T7
BP-801262Recombinant Cynomolgus IFNAR2 Protein, His-taggedHEK293CynomolgusHis
BP-801263Recombinant Human IFNAR2, GST-taggedE.coliHumanGST
BP-801264Recombinant Human IFNAR2, His-taggedHEK293HumanHis
BP-801265Recombinant Human IFNAR2, Fc-taggedHEK293HumanFc
BP-801266Recombinant Human IFNAR2 Protein, Fc-taggedHEK293HumanFc
BP-801267Recombinant Human IFNAR2, Fc ChimeraHuman 293 cells
BP-801268Recombinant Human IFNAR2, His-tagged
BP-801269Recombinant Human IFNAR2, His taggedHuman CellsHumanHis
BP-801270Recombinant Chicken IFNAR2Mammalian CellsChickenHis
BP-801271Recombinant Mouse IIFNAR2, Fc ChimeraNSO cellsMouseFc Chimera
BP-801272Recombinant Human Interferon(alpha, beta and omega) Receptor 2, Fc-taggedHuman CellsHumanFc
BP-801273Recombinant Mouse IFNAR2 ProteinMammalian CellsMouseHis

* PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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