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The IFNAR2 (Interferon alpha and beta receptor subunit 2) protein encoded by this gene is a type I membrane protein that forms one of the two chains of interferon α and β receptors. The binding and activation of receptors stimulate Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. In addition, the IFNAR2 cytoplasmic domain plays a role in connecting STAT4 to IFNAR and becomes a preassembled complex that can promote cytokine-driven STAT4 activation. In humans, the only heterodimer receptor complex composed of IFNAR1 and IFNAR2 mediates all cellular responses triggered by type I IFN. Studies have shown that IFNAR2 is necessary for anti-influenza immunity and can change the susceptibility to superinfection of post-influenza bacteria.
|Cat.No.||Product Name||Source||Species||Tag||Molecular Weight|
|BP-801261||Recombinant Human IFNAR2 protein, His & T7-tagged||E. coli||Human||His & T7|
|BP-801262||Recombinant Cynomolgus IFNAR2 Protein, His-tagged||HEK293||Cynomolgus||His|
|BP-801263||Recombinant Human IFNAR2, GST-tagged||E.coli||Human||GST|
|BP-801264||Recombinant Human IFNAR2, His-tagged||HEK293||Human||His|
|BP-801265||Recombinant Human IFNAR2, Fc-tagged||HEK293||Human||Fc|
|BP-801266||Recombinant Human IFNAR2 Protein, Fc-tagged||HEK293||Human||Fc|
|BP-801267||Recombinant Human IFNAR2, Fc Chimera||Human 293 cells|
|BP-801268||Recombinant Human IFNAR2, His-tagged|
|BP-801269||Recombinant Human IFNAR2, His tagged||Human Cells||Human||His|
|BP-801270||Recombinant Chicken IFNAR2||Mammalian Cells||Chicken||His|
|BP-801271||Recombinant Mouse IIFNAR2, Fc Chimera||NSO cells||Mouse||Fc Chimera|
|BP-801272||Recombinant Human Interferon(alpha, beta and omega) Receptor 2, Fc-tagged||Human Cells||Human||Fc|
|BP-801273||Recombinant Mouse IFNAR2 Protein||Mammalian Cells||Mouse||His|
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