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* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.
NEK3 (NIMA Related Kinase 3) belong to a large family of serine/threonine (Ser/Thr) kinases, which play an important role in coordinating microtubule dynamics during cilia development and mitosis. Diseases associated with NEK3 include muscle phosphorylase kinase deficiency and glycogen storage disease Ia. NEK3 regulates microtubule acetylation and promotes prolactin-mediated phosphorylation of PXN and VAV2 by affecting protein kinases that affect the morphology and polarity of neurons. It participates in the cytoskeleton recombination and movement of breast cancer cells mediated by prolactin by involving the mechanisms of RAC1 activation and PXN and VAV2 phosphorylation.
| Cat.No. | Product Name | Source | Species | Tag | Molecular Weight |
|---|---|---|---|---|---|
| BP-800562 | Recombinant Human NEK3 | ||||
| BP-800564 | Recombinant Mouse NEK3 Protein, GST & His-tagged | Baculovirus-Insect Cells | Mouse | GST & His |
* PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
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