NPC2 (Niemann-Pick Disease Type C2 Protein)

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NPC2 (Niemann-Pick Disease Type C2 Protein) is a lysosomal lumen protein that cooperates with NPC1 to mediate the efflux of LDL-derived cholesterol from the lysosome and plays a role in regulating cholesterol through the endosomal / lysosomal late system. The secretory form of NCP2 regulates bile cholesterol secretion by stimulating cholesterol transport mediated by ABCG5/ABCG8. The mutation of NCP2 is associated with Niemann-Pick Disease, Type C2 and Frontal Lobe Atrophy.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-801417Recombinant Mouse NPC2 ProteinMammalian CellsMouseHis
BP-801418Recombinant Human NPC2, His-taggedHEK293HumanHis
BP-801419Recombinant Human NPC2 protein, His & GST-taggedE. coliHumanHis & GST
BP-801420Recombinant Chicken NPC2Mammalian CellsChickenHis
BP-801421Recombinant Rhesus monkey NPC2 Protein, His-taggedMammalian CellsRhesus monkeyHis
BP-801422Recombinant Human NPC2, His-taggedHuman CellsHumanHis
BP-801423Recombinant Rat NPC2 protein, His-taggedHEK293RatHis
BP-801424Recombinant Human NPC2 Protein, GST-taggedWheat GermHumanGST
BP-801425Recombinant Zebrafish NPC2Mammalian CellsZebrafishHis

* PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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