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NPC2 (Niemann-Pick Disease Type C2 Protein) is a lysosomal lumen protein that cooperates with NPC1 to mediate the efflux of LDL-derived cholesterol from the lysosome and plays a role in regulating cholesterol through the endosomal / lysosomal late system. The secretory form of NCP2 regulates bile cholesterol secretion by stimulating cholesterol transport mediated by ABCG5/ABCG8. The mutation of NCP2 is associated with Niemann-Pick Disease, Type C2 and Frontal Lobe Atrophy.
|Cat.No.||Product Name||Source||Species||Tag||Molecular Weight|
|BP-801417||Recombinant Mouse NPC2 Protein||Mammalian Cells||Mouse||His|
|BP-801418||Recombinant Human NPC2, His-tagged||HEK293||Human||His|
|BP-801419||Recombinant Human NPC2 protein, His & GST-tagged||E. coli||Human||His & GST|
|BP-801420||Recombinant Chicken NPC2||Mammalian Cells||Chicken||His|
|BP-801421||Recombinant Rhesus monkey NPC2 Protein, His-tagged||Mammalian Cells||Rhesus monkey||His|
|BP-801422||Recombinant Human NPC2, His-tagged||Human Cells||Human||His|
|BP-801423||Recombinant Rat NPC2 protein, His-tagged||HEK293||Rat||His|
|BP-801424||Recombinant Human NPC2 Protein, GST-tagged||Wheat Germ||Human||GST|
|BP-801425||Recombinant Zebrafish NPC2||Mammalian Cells||Zebrafish||His|
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