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NUS1 (Nuclear Undecaprenyl Pyrophosphate Synthase 1 Homolog) encodes a subunit of dehydrodiphosphate diphosphate synthase (DHDDS). NUS1, together with DHDDS, is essential for protein glycosylation and plays an important role in the regulation of newborn lysosomal NPC2 proteins. Both NUS1 and DHDDS subunits contribute to enzyme activity by condensing multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodiphthaloyl diphosphate (Dedol-PP), a precursor of polyhydrophenol phosphate, which is used as a sugar carrier in protein glycosylation, endoplasmic reticulum (ER). NUS1 is associated with autosomal dominant development and epileptic encephalopathy.
|Cat.No.||Product Name||Source||Species||Tag||Molecular Weight|
|BP-801432||Recombinant Mouse NUS1 Protein||Mammalian Cells||Mouse||His|
|BP-801433||Recombinant Human NUS1, His-tagged||E.coli||Human||His|
|BP-801434||Recombinant Rhesus monkey NUS1 Protein, His-tagged||Mammalian Cells||Rhesus monkey||His|
|BP-801435||Recombinant Zebrafish NUS1||Mammalian Cells||Zebrafish||His|
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