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NUS1 (Nuclear Undecaprenyl Pyrophosphate Synthase 1 Homolog)

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NUS1 (Nuclear Undecaprenyl Pyrophosphate Synthase 1 Homolog) encodes a subunit of dehydrodiphosphate diphosphate synthase (DHDDS). NUS1, together with DHDDS, is essential for protein glycosylation and plays an important role in the regulation of newborn lysosomal NPC2 proteins. Both NUS1 and DHDDS subunits contribute to enzyme activity by condensing multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodiphthaloyl diphosphate (Dedol-PP), a precursor of polyhydrophenol phosphate, which is used as a sugar carrier in protein glycosylation, endoplasmic reticulum (ER). NUS1 is associated with autosomal dominant development and epileptic encephalopathy.

Cat.No.	Product Name	Source	Species	Tag
BP-801432	Recombinant Mouse NUS1 Protein	Mammalian Cells	Mouse	His
BP-801433	Recombinant Human NUS1, His-tagged	E.coli	Human	His
BP-801434	Recombinant Rhesus monkey NUS1 Protein, His-tagged	Mammalian Cells	Rhesus monkey	His
BP-801435	Recombinant Zebrafish NUS1	Mammalian Cells	Zebrafish	His

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