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PIN1 (Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1)

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* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

PIN1 (Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) has a molecular weight of 18KD and contains two domains: one is the N-terminal WW region composed of 39 amino acid residues, which mediates the binding of Pin1 to phosphorylated proteins, and the other is the C-terminal peptidyl prolyl cis-trans isomerase (PPIase) region, which consists of 120amino acid residues. The conformational changes induced by PIN1 will change the function and stability of the target protein. Studies have shown that out of control of Pin1 may play a key role in a variety of diseases. It is worth noting that the up-regulation of Pin1 is associated with some cancers, while the down-regulation of PIN1 is associated with Alzheimer's disease. Pin1 inhibitors may have therapeutic significance for cancer and immune diseases.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-801436Recombinant Zebrafish PIN1Mammalian CellsZebrafishHis
BP-801437Recombinant Mouse PIN1 protein, His-taggedE. coliMouseHis
BP-801438Recombinant Mouse PIN1 ProteinMammalian CellsMouseHis
BP-801439Recombinant Human PIN1, GST-taggedE.coliHumanGST
BP-801440Recombinant Human PIN1, T7-taggedE.Coli.
BP-801441Recombinant Human PIN1, His-taggedE. coli
BP-801442Recombinant Human PIN1E. coli
BP-801443Recombinant Human Peptidylprolyl Cis/trans Isomerase, NIMA-interacting 1Escherichia Coli.
BP-801444Recombinant Human PIN1, His taggedE. coliHumanHis
BP-801445Recombinant Human PIN1, None taggedE. coliHuman
BP-801446Recombinant Cynomolgus PIN1 Protein, His-taggedMammalian CellsCynomolgusHis
BP-801447Recombinant Human PTEN Induced Putative Kinase 1E. coliHumanN/A
BP-801448Recombinant Mouse Pink1 protein, His & T7-taggedE. coliMouseHis & T7

* PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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