PLK1 (polo-like kinase 1)

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Serine/threonine protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine protein kinase 13 (STPK13), is an enzyme encoded by PLK1 in humans. PLK1 plays an important role in the initiation, maintenance and completion of mitosis. PLK1 dysfunction may promote carcinogenesis and promote its progression. Overexpression of PLK1 has been found in many human cancers and is associated with poor prognosis of cancer. Many studies have shown that the inhibition of PLK1 can lead to cancer cell death by interfering with multiple stages of mitosis. Therefore, PLK1 is expected to become a potential target for cancer therapy. Diseases associated with PLK1 include gonococcal keratitis and gliomas.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-800637Recombinant Human Polo-Like Kinase 1, His-taggedHuman
BP-800638Recombinant Zebrafish PLK1Mammalian CellsZebrafishHis
BP-800639Recombinant Mouse Plk1, His taggedBaculovirus-Insect CellsMouseHis
BP-800640Recombinant Human Polo-like Kinase 1 (Drosophila)Baculovirus
BP-800641Recombinant Chicken PLK1Mammalian CellsChickenHis
BP-800642Recombinant Rat PLK1 ProteinMammalian CellsRatHis
BP-800643Recombinant Human PLK1 protein, MYC/DDK-taggedHEK293HumanMYC/DDK
BP-800644Recombinant Human PLK1 protein, Flag-tagged, BiotinylatedInsect cellHumanFlag
BP-800645Recombinant Human PLK1, His taggedBaculovirus-Insect CellsHumanHis

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