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PNMA1 (paraneoplastic Ma antigen 1)

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PNMA1 (paraneoplastic Ma antigen 1) gene encodes a pro-apoptotic protein that can induce anti-neuronal antibodies (anti-Ma) in patients with paraneoplastic neurological diseases. Nuclear and cytoplasmic expression in several cell types, most abundant in neurons. The higher expression of PNMA1 is closely related to the size of the tumor. Inhibition of endogenous PNMA1 expression reduces cell viability and promotes apoptosis. Studies have shown that PI3K/AKT, MAPK/ERK pathway and anti-apoptotic Bcl-2 family members may be involved in the survival-promoting and anti-apoptotic effects of PNMA1 on PDAC.

Cat.No.	Product Name	Source	Species	Tag
BP-801457	Recombinant Mouse PNMA1 Protein	Mammalian Cells	Mouse	His
BP-801458	Recombinant Human PNMA1, His-tagged	E. coli
BP-801459	Recombinant Rhesus monkey PNMA1 Protein, His-tagged	Mammalian Cells	Rhesus monkey	His
BP-801460	Recombinant Rat PNMA1 Protein	Mammalian Cells	Rat	His

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