PQBP1 (polyglutamine binding protein-1)

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PQBP1 (polyglutamine binding protein-1) is a highly conserved nuclear protein expressed in mesoderm and nuclear tissue. The PQBP1 gene that encodes this protein belongs to a disease-causing gene of mental disability, which is involved in the transcriptional and post-transcriptional regulation of gene expression in animals and even plants. This gene mutation can lead to X-linked mental retardation (XLID), is often referred to as Lempenning's syndrome. People with these disabilities have a series of common symptoms, including microcephaly, short stature and impaired intellectual development.

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