PSENEN (Presenilin Enhancer, Gamma-Secretase Subunit)

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PSENEN (presenilin enhancer, γ-secretase subunit) is a component of γ-secretase protein complex, which is necessary for the intramembrane processing of some type I transmembrane proteins, such as Notch protein and β-amyloid precursor protein. PSENEN is widely expressed in leukocyte, lung, placenta, small intestine, liver, kidney, spleen and thymus, skeletal muscle, heart and brain. Notch signaling is essential for the normal maturation and division of hair follicle cells and other types of skin cells. The processing of β-amyloid precursor protein produces neurotoxic amyloid beta peptide, which is the main component of senile plaque associated with Alzheimer's disease.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-801530Recombinant Zebrafish PSENENMammalian CellsZebrafishHis
BP-801531Recombinant Mouse PSENEN ProteinMammalian CellsMouseHis
BP-801532Recombinant Human PSENEN, GST-taggedE.coliHumanGST
BP-801533Recombinant Rhesus monkey PSENEN Protein, His-taggedMammalian CellsRhesus monkeyHis
BP-801534Recombinant Rat PSENEN ProteinMammalian CellsRatHis

* PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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