E3 ligase Ligand-Linker Conjugates 14 - CAS 1957236-21-3

E3 ligase Ligand-Linker Conjugates 14 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

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Molecular Formula
C25H31F3N4O11
Molecular Weight
620.53

E3 ligase Ligand-Linker Conjugates 14

    • Specification
      • Solubility
        DMSO : 50 mg/mL (ultrasonic)
        Storage
        Powder
        -20°C
        3 years



        4°C
        2 years


        In solvent
        -80°C
        6 months



        -20°C
        1 month
        Shipping
        Room temperature in continental US; may vary elsewhere
        Synonyms
        N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid; Thalidomide-O-amido-PEG3-C2-NH2 (TFA); Cereblon Ligand-Linker Conjugates 3 (TFA); E3 ligase Ligand-Linker Conjugates 14 (TFA)
    • Properties
      • InChI Key
        BLYRZYHKZRITLJ-UHFFFAOYSA-N
        InChI
        InChI=1S/C23H30N4O9.C2HF3O2/c24-6-8-33-10-12-35-13-11-34-9-7-25-19(29)14-36-17-3-1-2-15-20(17)23(32)27(22(15)31)16-4-5-18(28)26-21(16)30;3-2(4,5)1(6)7/h1-3,16H,4-14,24H2,(H,25,29)(H,26,28,30);(H,6,7)
        Canonical SMILES
        C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCOCCOCCOCCN.C(=O)(C(F)(F)F)O
Bio Calculators
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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
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