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t-Boc-N-amido-PEG8-amine - CAS 1052207-59-6

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t-Boc-N-amido-PEG8-amine is a cleavable 8-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

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Molecular Formula
C23H48N2O10
Molecular Weight
512.64

t-Boc-N-amido-PEG8-amine

    • Specification
      • Related CAS
        890091-42-6 (polymer) 198227-38-2 (polymer)
        Purity
        ≥95%
        Solubility
        Soluble in DCM, DMF, DMSO, Water
        Appearance
        Pale Yellow or Colorless Oily Matter
        Storage
        Store at 2-8°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
        Synonyms
        BocNH-PEG8-CH2CH2NH2; NHBoc-PEG8-amine; Boc-NH-PEG8-NH2; Boc-N-amido-PEG8-NH2; tert-Butyl (26-amino-3,6,9,12,15,18,21,24-octaoxahexacosyl)carbamate; 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanoic acid, 28-amino-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl (26-amino-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl)carbamate; Carbamic acid, N-(26-amino-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl)-, 1,1-dimethylethyl ester
    • Properties
      • Boiling Point
        579.4±50.0°C at 760 mmHg
        Density
        1.1±0.1 g/cm3
        InChI Key
        RJDFELJBUQILOQ-UHFFFAOYSA-N
        InChI
        InChI=1S/C23H48N2O10/c1-23(2,3)35-22(26)25-5-7-28-9-11-30-13-15-32-17-19-34-21-20-33-18-16-31-14-12-29-10-8-27-6-4-24/h4-21,24H2,1-3H3,(H,25,26)
        Canonical SMILES
        CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN
    • Preparing Stock Solutions
      • ConcentrationVolumeMass1 mg5 mg10 mg
        1 mM1.9507 mL9.7536 mL19.5072 mL
        5 mM0.3901 mL1.9507 mL3.9014 mL
        10 mM0.1951 mL0.9754 mL1.9507 mL
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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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