Thalidomide-NH-PEG1-NH2 hydrochloride - CAS 2154342-56-8

Thalidomide-NH-PEG1-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a PEG linker with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

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Molecular Formula
C₁₇H₂₁ClN₄O₅
Molecular Weight
396.83

Thalidomide-NH-PEG1-NH2 hydrochloride

    • Specification
      • Storage
        Store at -20°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        4-[2-(2-aminoethoxy)ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride
    • Properties
      • InChI Key
        LQYLHZFKGOZTOH-UHFFFAOYSA-N
        InChI
        1S/C17H20N4O5.ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23;/h1-3,12,19H,4-9,18H2,(H,20,22,23);1H
        Canonical SMILES
        NCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O.Cl
Bio Calculators
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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