Thalidomide-O-amido-C8-NH2 hydrochloride - CAS 2415263-07-7

Thalidomide-O-amido-C8-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C8 alkyl linker with terminal amine for covalent binding, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

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Molecular Formula
C₂₃H₃₁ClN₄O₆
Molecular Weight
494.97

Thalidomide-O-amido-C8-NH2 hydrochloride

    • Specification
      • Storage
        Desiccate at RT
        Shipping
        Room temperature in continental US; may vary elsewhere.
    • Properties
      • InChI Key
        KPPZEDZTBDIUJN-UHFFFAOYNA-N
        Canonical SMILES
        NCCCCCCCCNC(COC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O.Cl
        Pub Chem ID
        146018961
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