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MS177 - CAS 2225938-86-1

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MS177 is a potent and rapidly acting EZH2 degrader. It is a PROTAC molecule that combines a CRBN ligand, a linker, and an effective enzymatic EZH2 inhibitor C24 (C24 IC50: 12 nM). MS177 efficiently depletes EZH2-PRC2 and non-classical EZH2-cMyc complexes. It inhibits leukemia cell growth, induces apoptosis, and causes cell cycle arrest.

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Molecular Formula
C48H55N11O8
Molecular Weight
914.02

MS177

    • Specification
      • Appearance
        Solid
        Storage
        Store at -20°C
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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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