Thalidomide-O-C7-acid

 CAS No.: 2169266-70-8  Cat No.: BP-100132 4.5  

Thalidomide-O-C7-acid is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C7 alkyl linker with a terminal carboxylic acid, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand..

Thalidomide-O-C7-acid

Structure of 2169266-70-8

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C₂₁H₂₄N₂O₇
Molecular Weight
416.42

* For research and manufacturing use only. Not for human or clinical use.

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100 mg $678 In stock

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IUPACName
8-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyoctanoic acid
InChI Key
QFRXURXVZYAHGC-UHFFFAOYSA-N
InChI
1S/C21H24N2O7/c24-16-11-10-14(19(27)22-16)23-20(28)13-7-6-8-15(18(13)21(23)29)30-12-5-3-1-2-4-9-17(25)26/h6-8,14H,1-5,9-12H2,(H,25,26)(H,22,24,27)
Canonical SMILES
OC(CCCCCCCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O
Pub Chem ID
132212017

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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