t-Boc-N-amido-PEG2-amine

 CAS No.: 153086-78-3  Cat No.: BP-500009  Purity: ≥95% 4.5  

Boc-NH-PEG2-C2-NH2 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG2-C2-NH2 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG2-C2-NH2 is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs.

t-Boc-N-amido-PEG2-amine

Structure of 153086-78-3

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Category
PROTAC Linker
Molecular Formula
C11H24N2O4
Molecular Weight
248.32
Appearance
Light Yellow Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO (10 mm)
Appearance
Light Yellow Oily Liquid
Storage
Store at 2-8°C under inert gas (nitrogen or Argon)
Shipping
Room temperature in continental US; may vary elsewhere
IUPACName
tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
Synonyms
NHBoc-PEG2-amine; Boc-NH-PEG2-C2-NH2; BocNH-PEG2-CH2CH2NH2; N-(tert-Butoxycarbonyl)-3,6-dioxa-1,8-octanediaminetert-Butyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate; Boc-1-amino-3,6-dioxa-8-octanediamine; N-Boc-2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine; N-Boc-2,2'-(ethylenedioxy)diethylamine; N-Boc-3,6-dioxaoctane-1,8-diamine; Boc-N-amido-PEG2-Amine; N-Boc-3,6-dioxa-1,8-octanediamine; 1-(t-Butyloxycarbonyl-amino)-3,6-dioxa-8-octaneamine
Boiling Point
365.2±27.0°C (Predicted)
Density
1.046 g/mL at 20°C
InChI Key
OCUICOFGFQENAS-UHFFFAOYSA-N
InChI
InChI=1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14)
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCN

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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