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t-Boc-N-amido-PEG2-amine - CAS 153086-78-3

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Boc-NH-PEG2-C2-NH2 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG2-C2-NH2 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG2-C2-NH2 is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs.

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Molecular Formula
C11H24N2O4
Molecular Weight
248.32

t-Boc-N-amido-PEG2-amine

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO (10 mm)
        Appearance
        Light Yellow Oily Liquid
        Storage
        Store at 2-8°C under inert gas (nitrogen or Argon)
        Shipping
        Room temperature in continental US; may vary elsewhere
        IUPAC Name
        tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
        Synonyms
        NHBoc-PEG2-amine; Boc-NH-PEG2-C2-NH2; BocNH-PEG2-CH2CH2NH2; N-(tert-Butoxycarbonyl)-3,6-dioxa-1,8-octanediaminetert-Butyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate; Boc-1-amino-3,6-dioxa-8-octanediamine; N-Boc-2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine; N-Boc-2,2'-(ethylenedioxy)diethylamine; N-Boc-3,6-dioxaoctane-1,8-diamine; Boc-N-amido-PEG2-Amine; N-Boc-3,6-dioxa-1,8-octanediamine; 1-(t-Butyloxycarbonyl-amino)-3,6-dioxa-8-octaneamine
    • Properties
      • Boiling Point
        365.2±27.0°C (Predicted)
        Density
        1.046 g/mL at 20°C
        InChI Key
        OCUICOFGFQENAS-UHFFFAOYSA-N
        InChI
        InChI=1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14)
        Canonical SMILES
        CC(C)(C)OC(=O)NCCOCCOCCN
Bio Calculators
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Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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