- Advanced equipment and technique
- Experienced scientific team
- Highly reliable and reproducible result
- Data analysis, detailed report with results and discussion
- Quality one-stop service

2-(2-hydroxyethoxy)ethyl acetate - CAS 2093-20-1

Inquiry

2-(2-hydroxyethoxy)ethyl acetate is a polyethylene glycol (PEG)-based PROTAC linker. 2-(2-hydroxyethoxy)ethyl acetate can be used in the synthesis of a series of PROTACs.

* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

Molecular Formula

C6H12O4

Molecular Weight

148.157

2-(2-hydroxyethoxy)ethyl acetate

- Specification
  - Purity
    
    95%
    
    Appearance
    
    Liquid
    
    Storage
    
    Please store the product under the recommended conditions in the Certificate of Analysis.
    
    Shipping
    
    Room temperature in continental US; may vary elsewhere.
    
    IUPAC Name
    
    2-(2-hydroxyethoxy)ethyl acetate
    
    Synonyms
    
    Diethylene glycol monoacetate; PEG2-ethyl acetate
- Properties
  - Boiling Point
    
    231.0±15.0 °C at 760 mmHg
    
    Density
    
    1.1±0.1 g/cm3
    
    InChI Key
    
    XXXFZKQPYACQLD-UHFFFAOYSA-N
    
    InChI
    
    InChI=1S/C6H12O4/c1-6(8)10-5-4-9-3-2-7/h7H,2-5H2,1H3
    
    Canonical SMILES
    
    CC(=O)OCCOCCO
- Reference Reading
  - 1.Pyrimidine acyclic nucleosides, 1-[(2-Hydroxyethoxy)methyl]pyrimidines as candidate antivirals.
    
    Kelley JL, Kelsey JE, Hall WR, Krochmal MP, Schaeffer HJ. J Med Chem. 1981 Jun;24(6):753-6.
    
    A number of pyrimidine acyclic nucleosides were synthesized and tested for activity against herpes simplex virus type 1. Synthesis of 1-[(2-hydroxyethoxy)methyl]cytosine (8) and 1-[(2-hydroxyethoxy)methyl]uracil (14) was accomplished in two or three steps from 2,4-diethoxypyrimidine and 2-(benzoyloxy)ethoxymethyl chloride. The 5-methyl (20), 5-(trifluoromethyl) (21), and 5-fluoro (22) analogues of 14 were available in two steps form the appropriate bis(trimethylsilyl)ated 5-substituted uracil and 2-(acetoxymethoxy)ethyl acetate or 2-(benzoyloxy)ethoxymethyl chloride. Bromination of 8 and 14 or iodination of 14 gave the 5-halogeno-1-[(2-hydroxyethoxy)methyl]pyrimidines 9, 23, and 24. These pyrimidine acyclic nucleosides exhibited little or no activity against herpes simplex virus type 1 or against a range of other DNA and RNA viruses. This is compatible with their lack of substrate properties toward herpes simplex virus induced thymidine kinase.

Bio Calculators

Stock concentration: *

Desired final volume: *

Desired concentration: *

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂

Calculate

* Total Molecular Weight:

g/mol

Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳

Formula weight: *

g/mol

Desired final volume: *

Desired concentration: *