Propargyl-PEG8-amine

 CAS No.: 1196732-52-1  Cat No.: BP-500952  Purity: 98.0% 4.5  

Propargyl-PEG8-amine is an alkyne-functionalized PEG linker used for copper-free click chemistry in ADC construction. The PEG8 spacer improves hydrophilicity and flexibility, facilitating bioorthogonal payload conjugation for improved antibody-drug conjugate stability.

Propargyl-PEG8-amine

Structure of 1196732-52-1

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Category
PROTAC Linker
Molecular Formula
C19H37NO8
Molecular Weight
407.50
Appearance
Solid powder

* For research and manufacturing use only. Not for human or clinical use.

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Purity
98.0%
Solubility
10 mm in DMSO
Appearance
Solid powder
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at -5°C,keep in dry and avoid sunlight.
Shipping
-20°C (International: -20°C)
IUPACName
2-[2-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonyms
Propargyl-PEG8-amine; Propyne-PEG8-NH2
Boiling Point
477.4±40.0 °C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
HJYYOUVXTIUMEJ-UHFFFAOYSA-N
InChI
InChI=1S/C19H37NO8/c1-2-4-21-6-8-23-10-12-25-14-16-27-18-19-28-17-15-26-13-11-24-9-7-22-5-3-20/h1H,3-20H2
Canonical SMILES
C#CCOCCOCCOCCOCCOCCOCCOCCOCCN

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: mPEG11-amine | Benzyl-PEG11-Ms | Propargyl-PEG6-Br | Acid-PEG9-NHS ester | Iodo-PEG12-NHS ester | m-PEG15-amine | Azido-PEG6-amine | Aminooxy-PEG3-methane | Azido-PEG9-NHS ester | Propenyl-PEG3-Propenyl | Propargyl-PEG8-amine

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