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COOH-PEG6-COOMe - CAS 1807512-38-4

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COOH-PEG6-COOMe is a PEG linker containing a terminal carboxylic acid and a mono-methyl ester functional group. Methyl ester can be hydrolyzed under strongly basic conditions. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

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Molecular Formula
C17H32O10
Molecular Weight
396.43

COOH-PEG6-COOMe

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DCM, DMF, DMSO, Water
        Appearance
        Colorless Oily Matter
        Storage
        Store at 2-8°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        3-[2-[2-[2-[2-[2-(3-methoxy-3-oxopropoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
        Synonyms
        Carboxy-PEG6-mono-methyl ester; Acid-PEG6-mono-methyl ester; Acid-PEG6-Methyl Ester; 3-Oxo-2,6,9,12,15,18,21-heptaoxatetracosan-24-oic acid; 4,7,10,13,16,19-Hexaoxadocosane-1,22-dioic acid, monomethyl ester
    • Properties
      • Boiling Point
        503.7±50.0°C at 760 mmHg
        Density
        1.1±0.1 g/cm3
        InChI Key
        AQDNMXGBKPHQBA-UHFFFAOYSA-N
        InChI
        InChI=1S/C17H32O10/c1-21-17(20)3-5-23-7-9-25-11-13-27-15-14-26-12-10-24-8-6-22-4-2-16(18)19/h2-15H2,1H3,(H,18,19)
        Canonical SMILES
        COC(=O)CCOCCOCCOCCOCCOCCOCCC(=O)O
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