Pomalidomide-PEG4-Ph-NH2

 CAS No.: 1818885-63-0  Cat No.: BP-100067 4.5  

Pomalidomide-PEG4-Ph-NH2 incorporates a ligand for the E3 ubiquitin ligase, and a PROTAC linker, which bring together target protein and ubiquitinating machinery.

Pomalidomide-PEG4-Ph-NH2

Structure of 1818885-63-0

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C27H32N4O8
Molecular Weight
540.57

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
H2O : < 0.1 mg/mL;DMSO : ≥ 50 mg/mL
Storage
Pure form<br/>-20°C<br/>3 years<br/><br/><br/> <br/>4°C<br/>2 years<br/><br/><br/>In solvent<br/>-80°C<br/>6 months<br/><br/><br/> <br/>-20°C<br/>1 month
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Room temperature in continental US; may vary elsewhere
Synonyms
Pomalidomide-PEG4-Ph-NH2; Cereblon Ligand-Linker Conjugates 9; E3 Ligase Ligand-Linker Conjugates 2; 4-[2-[2-[2-[2-(4-aminophenoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
InChI Key
QTFDOBJYFQFDIO-UHFFFAOYSA-N
InChI
InChI=1S/C27H32N4O8/c28-18-4-6-19(7-5-18)39-17-16-38-15-14-37-13-12-36-11-10-29-21-3-1-2-20-24(21)27(35)31(26(20)34)22-8-9-23(32)30-25(22)33/h1-7,22,29H,8-17,28H2,(H,30,32,33)
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOC4=CC=C(C=C4)N

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: Azido-PEG8-NHS ester | TCO-PEG8-NHS ester | Pomalidomide-PEG4-Ph-NH2

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