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Fmoc-N-amido-PEG2-propionic acid - CAS 872679-70-4

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Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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Molecular Formula
C22H25NO6
Molecular Weight
399.44

Fmoc-N-amido-PEG2-propionic acid

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO, Methanol
        Appearance
        Colorless Oily Matter
        Storage
        Store at 2-8°C
        Shipping
        Room temperature
        IUPAC Name
        3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid
        Synonyms
        Fmoc-N-amido-PEG2-acid; Fmoc-9-Amino-4,7-Dioxanonanoic acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid; Fmoc-AEEP-OH; 13-(9H-Fluoren-9-yl)-11-oxo-4,7,12-trioxa-10-azatridecanoic Acid;?Fmoc-NH-PEG2-CH2CH2COOH; 9-(Fmoc-amino)-4,7-dioxanonanoic Acid; 2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-; Fmoc-NH-PEG2-COOH; Fmoc-NH-PEG2-acid; Fmoc-PEG2-propionic acid; 3-[2-[2-(Fmoc-amino)ethoxy]ethoxy]propionic Acid; 9-(9H-Fluorene-9-ylmethoxycarbonylamino)-4,7-dioxanonanoic acid
    • Properties
      • Boiling Point
        622.1±55.0°C at 760 mmHg
        Melting Point
        95.0-99.0°C
        Density
        1.243±0.06 g/cm3 at 20°C, 760 Torr
        InChI Key
        QWHLFJJLRVOHTM-UHFFFAOYSA-N
        InChI
        InChI=1S/C22H25NO6/c24-21(25)9-11-27-13-14-28-12-10-23-22(26)29-15-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-8,20H,9-15H2,(H,23,26)(H,24,25)
        Canonical SMILES
        C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCC(=O)O
        Biological Activity
        Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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