Fmoc-N-amido-PEG7-acid - CAS 1863885-74-8

Fmoc-N-amido-PEG7-acid is a PEG linker containing a Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be deprotected under the basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula
C32H45NO11
Molecular Weight
619.70

Fmoc-N-amido-PEG7-acid

    • Specification
      • Purity
        ≥95%
        Appearance
        Pale Yellow or Colorless Oily Liquid
        Storage
        Store at 2-8°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        3-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
        Synonyms
        Fmoc-NH-PEG7-CH2CH2COOH; Fmoc-PEG7-propionic acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25-octaoxa-4-azaoctacosan-28-oic acid; 2,7,10,13,16,19,22,25-Octaoxa-4-azaoctacosan-28-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-; Fmoc-N-PEG7-acid
    • Properties
      • Boiling Point
        758.0±60.0°C at 760 mmHg
        Density
        1.2±0.1 g/cm3
        InChI Key
        QTWMNLIXRWCJSM-UHFFFAOYSA-N
        InChI
        InChI=1S/C32H45NO11/c34-31(35)9-11-37-13-15-39-17-19-41-21-23-43-24-22-42-20-18-40-16-14-38-12-10-33-32(36)44-25-30-28-7-3-1-5-26(28)27-6-2-4-8-29(27)30/h1-8,30H,9-25H2,(H,33,36)(H,34,35)
        Canonical SMILES
        C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
Bio Calculators
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L

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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