Thalidomide-O-amido-PEG2-C2-NH2 (TFA)

 CAS No.: 1957235-75-4  Cat No.: BP-100073 4.5  

Thalidomide-O-amido-PEG2-C2-Amine trifluoroacetate is a PROTAC block consist of Thalidomide linked to PEG with an Amine functional group for conjugation reactions.

Thalidomide-O-amido-PEG2-C2-NH2 (TFA)

Structure of 1957235-75-4

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C23H27F3N4O10
Molecular Weight
576.48

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
10 mM in DMSO;H2O : ≥ 150 mg/mL
Storage
4°C, sealed storage, away from moisture<br/>*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Shipping
Room temperature in continental US; may vary elsewhere
Synonyms
Thalidomide-O-amido-PEG2-C2-NH2 (TFA); Cereblon Ligand-Linker Conjugates 10 (TFA); E3 Ligase Ligand-Linker Conjugates 24 (TFA); Thalidomide-O-amido-PEG2-C2-Amine Trifluoroacetate; N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid
InChI Key
JQWXWSIQGKGHEB-UHFFFAOYSA-N
InChI
InChI=1S/C21H26N4O8.C2HF3O2/c22-6-8-31-10-11-32-9-7-23-17(27)12-33-15-3-1-2-13-18(15)21(30)25(20(13)29)14-4-5-16(26)24-19(14)28;3-2(4,5)1(6)7/h1-3,14H,4-12,22H2,(H,23,27)(H,24,26,28);(H,6,7)
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCOCCOCCN.C(=O)(C(F)(F)F)O

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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