Azido-PEG4-acetic Acid

 CAS No.: 201467-81-4  Cat No.: BP-500016  Purity: ≥95% 4.5  

N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units. N33-TEG-COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Azido-PEG4-acetic Acid

Structure of 201467-81-4

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Category
PROTAC Linker
Molecular Formula
C10H19N3O6
Molecular Weight
277.27
Appearance
Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO, Water
Appearance
Liquid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere
IUPACName
2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]acetic acid
Synonyms
Azido-PEG4-CH2CO2H;Azido-PEG4-CH2COOH; N3-TEG-COOH; N3-PEG4-CH2COOH; 14-azido-3,6,9,12-tetraoxatetradecanoic acid; Acetic acid, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-; 14-azido-3,6,9,12-tetraoxatetradecan-1-oic acid
Density
0.750-0.850 g/mL at 20°C
InChI Key
YHTABJLSZLHRFV-UHFFFAOYSA-N
InChI
InChI=1S/C10H19N3O6/c11-13-12-1-2-16-3-4-17-5-6-18-7-8-19-9-10(14)15/h1-9H2,(H,14,15)
Canonical SMILES
C(COCCOCCOCCOCC(=O)O)N=[N+]=[N-]

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Aminoxy-PEG4-acid | Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane | DSPE-PEG36-mal | Azido-PEG6-alcohol | Bis-Mal-PEG7 | CHO-Ph-CONH-PEG2-amine | m-PEG37-acid | N-Boc-amino-PEG3-acid | Mal-amido-PEG9-NHS ester | Hydroxy-PEG7-acetic acid | Azido-PEG4-acetic Acid

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