Tos-PEG2-O-CH2COOH - CAS 1807537-35-4

Tos-PEG2-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula
C13H18O7S
Molecular Weight
318.34

Tos-PEG2-O-CH2COOH

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO
        Storage
        Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]acetic acid
        Synonyms
        2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetic acid; Tos-PEG3-CH2CO2H; Tos-PEG3-CH2COOH; Tos-PEG2-CH2COOH; Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-; [2-(2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]acetic acid
    • Properties
      • Boiling Point
        512.8±40.0°C (Predicted)
        Density
        1.306±0.06 g/cm3 (Predicted)
        InChI Key
        QQHWSZBWDYTXGD-UHFFFAOYSA-N
        InChI
        InChI=1S/C13H18O7S/c1-11-2-4-12(5-3-11)21(16,17)20-9-8-18-6-7-19-10-13(14)15/h2-5H,6-10H2,1H3,(H,14,15)
        Canonical SMILES
        CC1=CC=C(S(=O)(OCCOCCOCC(O)=O)=O)C=C1
Bio Calculators
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