Tos-PEG3-O-CH2COOH

 CAS No.: 1581248-63-6  Cat No.: BP-500275  Purity: ≥95% 4.5  

Tos-PEG3-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Tos-PEG3-O-CH2COOH

Structure of 1581248-63-6

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PROTAC Linker
Molecular Formula
C15H22O8S
Molecular Weight
362.41

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid
Synonyms
Tos-PEG4-CH2CO2H; Tos-PEG4-CH2COOH; Tos-PEG3-CH2COOH; 2-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)acetic acid; {2-[2-(2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]ethoxy}acetic acid; Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-
Boiling Point
539.9±45.0°C at 760 mmHg
Density
1.3±0.1 g/cm3
InChI Key
BOUJNGOUZPSTFF-UHFFFAOYSA-N
InChI
InChI=1S/C15H22O8S/c1-13-2-4-14(5-3-13)24(18,19)23-11-10-21-7-6-20-8-9-22-12-15(16)17/h2-5H,6-12H2,1H3,(H,16,17)
Canonical SMILES
CC1=CC=C(S(=O)(OCCOCCOCCOCC(O)=O)=O)C=C1

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Hydroxy-PEG3-C2-PFP ester | 1,3-Dibromo-5,5-dimethylhydantoin | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) | THP-PEG8-THP | Bromo-PEG3-CH2COOtBu | Mal-PEG2-NH2 | AcS-PEG6-t-butyl ester | m-PEG4-CH2-methyl ester | DBCO-(PEG2-Val-Cit-PAB)2 | Acid-PEG3-t-butyl ester | Tos-PEG3-O-CH2COOH

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