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Tos-PEG3-O-CH2COOH - CAS 1581248-63-6

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Tos-PEG3-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula
C15H22O8S
Molecular Weight
362.41

Tos-PEG3-O-CH2COOH

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DCM
        Storage
        Store at 2-8°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid
        Synonyms
        Tos-PEG4-CH2CO2H; Tos-PEG4-CH2COOH; Tos-PEG3-CH2COOH; 2-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)acetic acid; {2-[2-(2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]ethoxy}acetic acid; Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-
    • Properties
      • Boiling Point
        539.9±45.0°C at 760 mmHg
        Density
        1.3±0.1 g/cm3
        InChI Key
        BOUJNGOUZPSTFF-UHFFFAOYSA-N
        InChI
        InChI=1S/C15H22O8S/c1-13-2-4-14(5-3-13)24(18,19)23-11-10-21-7-6-20-8-9-22-12-15(16)17/h2-5H,6-12H2,1H3,(H,16,17)
        Canonical SMILES
        CC1=CC=C(S(=O)(OCCOCCOCCOCC(O)=O)=O)C=C1
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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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