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Tos-PEG6-THP - CAS 669556-37-0

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Tos-PEG6-THP is a PEG linker with a tosyl moiety and THP protecting group. It is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. THP is an alcohol protection group that can be removed under acidic conditions. Tosyl is an excellent leaving group for nucleophilic substitution reaction.

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Molecular Formula
C24H40O10S
Molecular Weight
520.63

Tos-PEG6-THP

    • Specification
      • Purity
        ≥95%
        Storage
        Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
        Synonyms
        THP-PEG8-Tos; 2-((3-tosyl-3γ3,4,7,10,13,16-hexaoxaoctadecan-18-yl)oxy)tetrahydro-2H-pyran
    • Properties
      • Boiling Point
        613.1±55.0 °C at 760 mmHg
        Density
        1.2±0.1 g/cm3
        InChI Key
        QGSBMQZFPAVLBB-UHFFFAOYSA-N
        InChI
        InChI=1S/C24H40O10S/c1-22-5-7-23(8-6-22)35(25,26)34-21-19-31-17-15-29-13-11-27-10-12-28-14-16-30-18-20-33-24-4-2-3-9-32-24/h5-8,24H,2-4,9-21H2,1H3
        Canonical SMILES
        O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCCOCCOC2OCCCC2)=O
Bio Calculators
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Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
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