Tos-PEG6-THP

 CAS No.: 669556-37-0  Cat No.: BP-500889  Purity: ≥95% 4.5  

Tos-PEG6-THP is a PEG linker with a tosyl moiety and THP protecting group. It is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. THP is an alcohol protection group that can be removed under acidic conditions. Tosyl is an excellent leaving group for nucleophilic substitution reaction.

Tos-PEG6-THP

Structure of 669556-37-0

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Category
PROTAC Linker
Molecular Formula
C24H40O10S
Molecular Weight
520.63

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Synonyms
THP-PEG8-Tos; 2-((3-tosyl-3γ3,4,7,10,13,16-hexaoxaoctadecan-18-yl)oxy)tetrahydro-2H-pyran
Boiling Point
613.1±55.0 °C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
QGSBMQZFPAVLBB-UHFFFAOYSA-N
InChI
InChI=1S/C24H40O10S/c1-22-5-7-23(8-6-22)35(25,26)34-21-19-31-17-15-29-13-11-27-10-12-28-14-16-30-18-20-33-24-4-2-3-9-32-24/h5-8,24H,2-4,9-21H2,1H3
Canonical SMILES
O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCCOCCOC2OCCCC2)=O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: mPEG5-bromide | Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid | DBCO-PEG4-triethoxysilane | COOH-PEG1-COOtBu | Thiol-C10-amide-PEG8 | Ms-PEG3-CH2CH2COOH | Azido-PEG5-propionic acid | Propargyl-PEG2-NHS ester | Propargyl-PEG8-NHS ester | Propargyl-PEG1-COOtBu | Tos-PEG6-THP

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