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Fmoc-N-amido-PEG10-propionic acid - CAS 2101563-45-3

Inquiry

Fmoc-N-amido-PEG10-propionic acid is a PEG linker containing a Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be deprotected under the basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula

C38H57NO14

Molecular Weight

751.86

Fmoc-N-amido-PEG10-propionic acid

- Specification
  - Purity
    
    >97%
    
    Appearance
    
    Pale Yellow or Colorless Oily Liquid
    
    Storage
    
    Store at 2-8°C
    
    Shipping
    
    Room temperature in continental US; may vary elsewhere.
    
    IUPAC Name
    
    3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
    
    Synonyms
    
    Fmoc-N-amido-PEG10-acid; Fmoc-NH-PEG10-CH2CH2COOH; Fmoc-NH-PEG10-acid; Fmoc-PEG10-propionic acid; Fmoc-NH-PEG10-propionic acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34-undecaoxa-4-azaheptatriacontan-37-oic acid; 5,8,11,14,17,20,23,26,29,32-Decaoxa-2-azapentatriacontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 2,7,10,13,16,19,22,25,28,31,34-Undecaoxa-4-azaheptatriacontan-37-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
- Properties
  - Boiling Point
    
    826.4±65.0 °C at 760 mmHg
    
    Density
    
    1.2±0.1 g/cm3
    
    InChI Key
    
    NAILXQLIMFAMGQ-UHFFFAOYSA-N
    
    InChI
    
    InChI=1S/C38H57NO14/c40-37(41)9-11-43-13-15-45-17-19-47-21-23-49-25-27-51-29-30-52-28-26-50-24-22-48-20-18-46-16-14-44-12-10-39-38(42)53-31-36-34-7-3-1-5-32(34)33-6-2-4-8-35(33)36/h1-8,36H,9-31H2,(H,39,42)(H,40,41)
    
    Canonical SMILES
    
    C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

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