Fmoc-N-amido-PEG10-propionic acid

 CAS No.: 2101563-45-3  Cat No.: BP-501338  Purity: >97% 4.5  

Fmoc-N-amido-PEG10-propionic acid is a PEG linker containing a Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be deprotected under the basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Fmoc-N-amido-PEG10-propionic acid

Structure of 2101563-45-3

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PROTAC Linker
Molecular Formula
C38H57NO14
Molecular Weight
751.86
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>97%
Appearance
Pale Yellow or Colorless Oily Liquid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
Fmoc-N-amido-PEG10-acid; Fmoc-NH-PEG10-CH2CH2COOH; Fmoc-NH-PEG10-acid; Fmoc-PEG10-propionic acid; Fmoc-NH-PEG10-propionic acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34-undecaoxa-4-azaheptatriacontan-37-oic acid; 5,8,11,14,17,20,23,26,29,32-Decaoxa-2-azapentatriacontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 2,7,10,13,16,19,22,25,28,31,34-Undecaoxa-4-azaheptatriacontan-37-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
Boiling Point
826.4±65.0 °C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
NAILXQLIMFAMGQ-UHFFFAOYSA-N
InChI
InChI=1S/C38H57NO14/c40-37(41)9-11-43-13-15-45-17-19-47-21-23-49-25-27-51-29-30-52-28-26-50-24-22-48-20-18-46-16-14-44-12-10-39-38(42)53-31-36-34-7-3-1-5-32(34)33-6-2-4-8-35(33)36/h1-8,36H,9-31H2,(H,39,42)(H,40,41)
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: 1-Isothiocyanato-PEG3-azide | N,N'-DME-N-PEG2-Boc | 2-Propenoic acid,2-[2-(2-hydroxyethoxy)ethoxy]ethyl ester | 2-[2-(Prop-2-yn-1-yloxy)ethoxy]acetic acid | Tos-PEG3-t-butyl ester | Tos-PEG3-C2-methyl ester | N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 | TCO-PEG4-DBCO | Br-PEG8-COOtBu | Tetraethyl heptane-1,7-diylbis(phosphonate) | Fmoc-N-amido-PEG10-propionic acid

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