L-Homopropargylglycine hydrochloride - CAS 942518-19-6

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L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor. HPG-labeling is a fast, sensitive, non-toxic, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.

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Molecular Formula

C6H10ClNO2

Molecular Weight

163.60

L-Homopropargylglycine hydrochloride

- Specification
  - Solubility
    
    In DMSO: 125 mg/mL (764.06 mM; Need ultrasonic)
    
    Appearance
    
    White to Off-white Solid
    
    Storage
    
    -20°C, sealed storage, away from moisture; In solvent, -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
    
    Shipping
    
    Room temperature in continental US; may vary elsewhere.
    
    IUPAC Name
    
    (2S)-2-aminohex-5-ynoic acid;hydrochloride
    
    Synonyms
    
    L-Homopropargylglycine (hydrochloride); HPG hydrochloride
- Properties
  - InChI Key
    
    XGBWOGGSQVMSRX-JEDNCBNOSA-N
    
    InChI
    
    InChI=1S/C6H9NO2.ClH/c1-2-3-4-5(7)6(8)9;/h1,5H,3-4,7H2,(H,8,9);1H/t5-;/m0./s1
    
    Canonical SMILES
    
    C#CCCC(C(=O)O)N.Cl
- Preparing Stock Solutions
  - ConcentrationVolumeMass 1 mg 5 mg 10 mg
    
    1 mM 6.1125 mL 30.5623 mL 61.1247 mL
    
    5 mM 1.2225 mL 6.1125 mL 12.2249 mL
    
    10 mM 0.6112 mL 3.0562 mL 6.1125 mL

ConcentrationVolumeMass	1 mg	5 mg	10 mg
1 mM	6.1125 mL	30.5623 mL	61.1247 mL
5 mM	1.2225 mL	6.1125 mL	12.2249 mL
10 mM	0.6112 mL	3.0562 mL	6.1125 mL

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