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Mal-PEG2-acid - CAS 1374666-32-6

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Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule.

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Molecular Formula
C11H15NO6
Molecular Weight
257.24

Mal-PEG2-acid

    • Specification
      • Related CAS
        357277-61-3 (polymer) 2422928-26-3 (polymer)
        Purity
        ≥95%
        Solubility
        Soluble in DMSO (10 mm)
        Appearance
        White to Light Yellow Powder to Crystal
        Shelf Life
        0-4°C for short term (days to weeks), or -20°C for long term (months).
        Storage
        Store at 2-8°C
        Shipping
        Room temperature, or blue ice upon request.
        IUPAC Name
        3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid
        Synonyms
        Mal-PEG2-CH2CH2COOH; Maleimide-PEG2-CH2CH2COOH; Mal-PEG2-COOH; Mal-PEG2-propionic acid; 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoic acid; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-
    • Properties
      • Boiling Point
        455.7±35.0 °C at 760 mmHg
        Density
        1.329±0.06 g/cm3 (Predicted)
        InChI Key
        TXMDOUPVKVGPIS-UHFFFAOYSA-N
        InChI
        InChI=1S/C11H15NO6/c13-9-1-2-10(14)12(9)4-6-18-8-7-17-5-3-11(15)16/h1-2H,3-8H2,(H,15,16)
        Canonical SMILES
        C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O
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