Mal-PEG2-acid

 CAS No.: 1374666-32-6  Cat No.: BP-500326  Purity: ≥95% 4.5  

Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule.

Mal-PEG2-acid

Structure of 1374666-32-6

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PROTAC Linker
Molecular Formula
C11H15NO6
Molecular Weight
257.24
Appearance
White to Light Yellow Powder to Crystal

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO (10 mm)
Appearance
White to Light Yellow Powder to Crystal
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at 2-8°C
Shipping
Room temperature, or blue ice upon request.
IUPACName
3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid
Synonyms
Mal-PEG2-CH2CH2COOH; Maleimide-PEG2-CH2CH2COOH; Mal-PEG2-COOH; Mal-PEG2-propionic acid; 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoic acid; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-
Boiling Point
455.7±35.0 °C at 760 mmHg
Density
1.329±0.06 g/cm3 (Predicted)
InChI Key
TXMDOUPVKVGPIS-UHFFFAOYSA-N
InChI
InChI=1S/C11H15NO6/c13-9-1-2-10(14)12(9)4-6-18-8-7-17-5-3-11(15)16/h1-2H,3-8H2,(H,15,16)
Canonical SMILES
C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: MAL-Di-EG-OPFP | 4,7,10,13,16,19,22,25,28-Nonaoxahentriaconta-1,30-diyne | Thiol-PEG5-amine | DSPE-PEG2-mal | Azido-PEG6-azide | FmocNH-PEG4-t-butyl acetate | Bis-acrylate-PEG6 | Boc-aminoxy-PEG4-acid | Maleimide-NH-PEG4-CH2CH2COOPFP Ester | TCO-PEG4-acid | Mal-PEG2-acid

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