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Mal-PEG3-PFP ester - CAS 1807534-78-6

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Mal-PEG3-PFP ester is a PEG linker containing maleimide and PFP moieties. Maleimide is thiol-reactive and reacts between pH 6.5 and 7.5 to form thiol ester bonds. PFP moiety is amine-reactive and is less susceptible to undergoing hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.

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Molecular Formula
C19H18F5NO7
Molecular Weight
467.35

Mal-PEG3-PFP ester

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DCM, DMF, DMSO
        Storage
        Store at 2-8°C
        Shipping
        Room temperature
        IUPAC Name
        (2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]propanoate
        Synonyms
        Mal-PEG3-PFP; Perfluorophenyl 3-(2-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
    • Properties
      • Boiling Point
        531.5±50.0°C (Predicted)
        Density
        1.438±0.06 g/cm3 (Predicted)
        InChI Key
        NTHCDRJWHPEQDJ-UHFFFAOYSA-N
        InChI
        InChI=1S/C19H18F5NO7/c20-14-15(21)17(23)19(18(24)16(14)22)32-13(28)3-5-29-7-9-31-10-8-30-6-4-25-11(26)1-2-12(25)27/h1-2H,3-10H2
        Canonical SMILES
        C1=CC(=O)N(C1=O)CCOCCOCCOCCC(=O)OC2=C(C(=C(C(=C2F)F)F)F)F
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