Mal-PEG3-PFP ester

 CAS No.: 1807534-78-6  Cat No.: BP-500402  Purity: ≥95% 4.5  

Mal-PEG3-PFP ester is a PEG linker containing maleimide and PFP moieties. Maleimide is thiol-reactive and reacts between pH 6.5 and 7.5 to form thiol ester bonds. PFP moiety is amine-reactive and is less susceptible to undergoing hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.

Mal-PEG3-PFP ester

Structure of 1807534-78-6

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PROTAC Linker
Molecular Formula
C19H18F5NO7
Molecular Weight
467.35

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO
Storage
Store at 2-8°C
Shipping
Room temperature
IUPACName
(2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]propanoate
Synonyms
Mal-PEG3-PFP; Perfluorophenyl 3-(2-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
Boiling Point
531.5±50.0°C (Predicted)
Density
1.438±0.06 g/cm3 (Predicted)
InChI Key
NTHCDRJWHPEQDJ-UHFFFAOYSA-N
InChI
InChI=1S/C19H18F5NO7/c20-14-15(21)17(23)19(18(24)16(14)22)32-13(28)3-5-29-7-9-31-10-8-30-6-4-25-11(26)1-2-12(25)27/h1-2H,3-10H2
Canonical SMILES
C1=CC(=O)N(C1=O)CCOCCOCCOCCC(=O)OC2=C(C(=C(C(=C2F)F)F)F)F

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: m-PEG10-COOH | N-DBCO-N-bis(PEG2-C2-NHS ester) | Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA | Monoethyl Pimelate | Tos-PEG9-COOtBu | 3,7-Dioxa-1,9-nonanediol | Tos-PEG7-COOtBu | Tos-PEG3-CH2COOtBu | Tos-PEG2-CH2-Boc | PEG7-O-Ms | Mal-PEG3-PFP ester

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