Nonoxynol-5 - CAS 20636-48-0

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BP-501502 1 g $1099 In stock
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Nonylbenzene-PEG5-OH is a polyethylene glycol (PEG)-based PROTAC linker. Nonylbenzene-PEG5-OH can be used in the synthesis of a series of PROTACs.

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Molecular Formula
C25H44O6
Molecular Weight
440.61

Nonoxynol-5

    • Specification
      • Storage
        Please store the product under the recommended conditions in the Certificate of Analysis.
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        2-[2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
    • Properties
      • InChI Key
        PITRRWWILGYENJ-UHFFFAOYSA-N
        InChI
        InChI=1S/C25H44O6/c1-2-3-4-5-6-7-8-9-24-10-12-25(13-11-24)31-23-22-30-21-20-29-19-18-28-17-16-27-15-14-26/h10-13,26H,2-9,14-23H2,1H3
        Canonical SMILES
        CCCCCCCCCC1=CC=C(C=C1)OCCOCCOCCOCCOCCO
    • Reference Reading
      • 1. A modified transmembrane migration method for evaluating the spermicidal potency of some nonoxynol compounds
        P B Curtis-Prior, A L Gadd J Pharm Pharmacol . 1988 Mar;40(3):215-6. doi: 10.1111/j.2042-7158.1988.tb05225.x.
        The transmembrane migration technique, a simple method in-vitro for quantitatively assessing the effects of a drug on human sperm motility, has been evaluated. The original method has been modified to include a preincubation step, and the incubation time has been reduced to 90 min. In semen samples possessing sperm concentrations of less than 75 x 12(6) spermatozoa mL-1 the volume of the lower reservoir has been reduced to 1 mL. This modified method has been used to compare the spermicidal potency of the widely employed non-ionic surfactant nonoxynol-9, with nonoxynol-5 and nonoxynol-15 (containing, respectively, fewer and more ethylene oxide units per molecule). The rank order of spermicidal potency of the compounds evaluated was nonoxynol-9 = nonoxynol-5 greater than nonoxynol-15.
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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
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