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Pomalidomide-d5 - CAS 1377838-49-7

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Pomalidomide-d5 is a deuterated form of Pomalidomide. Pomalidomide is a third-generation immunomodulatory agent that functions as a molecular glue. It interacts with E3 ligase cereblon and induces the degradation of the essential Ikaros transcription factor.

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Molecular Formula
C13H6D5N3O4
Molecular Weight
278.27

Pomalidomide-d5

    • Specification
      • Purity
        95% by HPLC; 95% atom D
        Solubility
        DMF: 10 mg/ml; DMSO: 15 mg/ml
        Storage
        Store at -20°C
        IUPAC Name
        4-amino-2-(3,4,4,5,5-pentadeuterio-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
        Synonyms
        Pomalidomide D5
    • Properties
      • Boiling Point
        582.9±45.0 °C at 760 mmHg
        Density
        1.6±0.1 g/cm3
        InChI Key
        UVSMNLNDYGZFPF-XHNMXOBISA-N
        InChI
        InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)/i4D2,5D2,8D
        Canonical SMILES
        C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
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