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Pomalidomide-PEG4-azide - CAS 2271036-47-4

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Pomalidomide-PEG4-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a PEG4 linker with terminal azide, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

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Molecular Formula
C₂₃H₃₀N₆O₈
Molecular Weight
518.52

Pomalidomide-PEG4-azide

    • Specification
      • Solubility
        In DMSO: 33.33 mg/mL (64.28 mM; Need ultrasonic)
        Storage
        -20°C, protect from light; In solvent, -80°C, 6 months; -20°C, 1 month (protect from light)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        4-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
    • Properties
      • InChI Key
        SMHKJRVPSDESLS-UHFFFAOYSA-N
        InChI
        1S/C23H30N6O8/c24-28-26-7-9-35-11-13-37-15-14-36-12-10-34-8-6-25-17-3-1-2-16-20(17)23(33)29(22(16)32)18-4-5-19(30)27-21(18)31/h1-3,18,25H,4-15H2,(H,27,30,31)
        Canonical SMILES
        [N-]=[N+]=NCCOCCOCCOCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O
        Pub Chem ID
        145714646
Bio Calculators
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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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