Pomalidomide-PEG4-azide

 CAS No.: 2271036-47-4  Cat No.: BP-100097 4.5  

Pomalidomide-PEG4-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a PEG4 linker with terminal azide, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

Pomalidomide-PEG4-azide

Structure of 2271036-47-4

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C₂₃H₃₀N₆O₈
Molecular Weight
518.52

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
In DMSO: 33.33 mg/mL (64.28 mM; Need ultrasonic)
Storage
-20°C, protect from light; In solvent, -80°C, 6 months; -20°C, 1 month (protect from light)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
4-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
InChI Key
SMHKJRVPSDESLS-UHFFFAOYSA-N
InChI
1S/C23H30N6O8/c24-28-26-7-9-35-11-13-37-15-14-36-12-10-34-8-6-25-17-3-1-2-16-20(17)23(33)29(22(16)32)18-4-5-19(30)27-21(18)31/h1-3,18,25H,4-15H2,(H,27,30,31)
Canonical SMILES
[N-]=[N+]=NCCOCCOCCOCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O
Pub Chem ID
145714646

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: HO-PEG8-OH | Pomalidomide-PEG2-CO2H | MS177 | Benzyl-PEG2-ethoxyethane-PEG2 | Pomalidomide-C8-NH2 | Azido-PEG4-hydrazide | Boc-C1-PEG2-C4-Cl | Mal-PEG6-acid | Azido-PEG6-NHS ester | Hydroxy-PEG8-t-butyl ester | Pomalidomide-PEG4-azide

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