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Pomalidomide-PEG4-C2-NH2 hydrochloride - CAS 2357105-92-9

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Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 4 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

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Molecular Formula
C₂₃H₃₃ClN₄O₈
Molecular Weight
528.98

Pomalidomide-PEG4-C2-NH2 hydrochloride

    • Specification
      • Storage
        Store at -20°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        4-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride
        Synonyms
        Pomalidomide - linker 8
    • Properties
      • InChI
        1S/C23H32N4O8.ClH/c24-6-8-32-10-12-34-14-15-35-13-11-33-9-7-25-17-3-1-2-16-20(17)23(31)27(22(16)30)18-4-5-19(28)26-21(18)29;/h1-3,18,25H,4-15,24H2,(H,26,28,29);1H
        Canonical SMILES
        O=C(N(C(C1=CC=C2)=O)C3CCC(NC3=O)=O)C1=C2NCCOCCOCCOCCOCCN.Cl
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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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