VH032-PEG5-C6-Cl

 CAS No.: 1799506-06-1  Cat No.: BP-400039 4.5  

VH032-PEG5-C6-Cl, a chloroalkane-containing PROTAC, induces degradation of HaloTag fusion proteins. VH032-PEG5-C6-Cl is a PROTAC block consist of VH032 and a linker with chlorine functional group for conjugation reactions.

VH032-PEG5-C6-Cl

Structure of 1799506-06-1

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C38H59ClN4O9S
Molecular Weight
783.41

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
DMSO : ≥ 50 mg/mL
Storage
-20°C, protect from light<br/>*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Shipping
Room temperature in continental US; may vary elsewhere
Synonyms
VH032-PEG5-C6-Cl; HaloPROTAC 2; N-[2-[[2-[2-[2-[2-[2-(6-chlorohexoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-1-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
InChI Key
XWSLAICADDJNNG-UHFFFAOYSA-N
InChI
InChI=1S/C38H59ClN4O9S/c1-28-34(53-27-40-28)30-11-9-29(10-12-30)24-43-25-31(44)23-32(43)36(46)42-37(47)35(38(2,3)4)41-33(45)26-52-22-21-51-20-19-50-18-17-49-16-15-48-14-8-6-5-7-13-39/h9-12,27,31-32,35,44H,5-8,13-26H2,1-4H3,(H,41,45)(H,42,46,47)
Canonical SMILES
CC1=C(SC=N1)C2=CC=C(C=C2)CN3CC(CC3C(=O)NC(=O)C(C(C)(C)C)NC(=O)COCCOCCOCCOCCOCCCCCCCl)O

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: m-PEG11-COOH | 2-(2,6-Dioxopiperidin-3-yl)-4-((9-hydroxynonyl)oxy)isoindoline-1,3-dione | N3-PEG3-Propanehydrazide | Boc-AEA DCHA | Mal-amido-PEG24-TFP ester | H2N-PEG5-Hydrazide | N-Boc-4,7,10-Trioxa-1,13-tridecanediamine | Azido-PEG4-propionic acid | Fmoc-N-amido-PEG3-acetic acid | C-NH-Boc-C-Bis-(C-PEG1-Boc) | VH032-PEG5-C6-Cl

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