(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

 CAS No.: 1835705-61-7  Cat No.: BP-100071 4.5  

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl is a synthesized compound which incorporates a ligand for the E3 ubiquitin ligase and a PROTAC linker to bring together target protein and ubiquitinating machinery.

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

Structure of 1835705-61-7

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C39H61ClN4O6S
Molecular Weight
749.44

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
10 mM in DMSO
Storage
Pure form<br/>-20°C<br/>3 years<br/><br/><br/><br/>In solvent<br/>-80°C<br/>6 months<br/><br/><br/> <br/>-20°C<br/>1 month
Shipping
Room temperature in continental US; may vary elsewhere
Synonyms
(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl; VHL Ligand-Linker Conjugates 11; E3 ligase Ligand-Linker Conjugates 11; VH032-ketone-(C3-PEG)2-C6-Cl; (2S,4R)-1-[(2S)-2-[6-[5-(6-chlorohexoxy)pentoxy]hexanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
InChI Key
DVLICOWBWULAJJ-RWTOGVPBSA-N
InChI
InChI=1S/C39H61ClN4O6S/c1-29-35(51-28-42-29)31-18-16-30(17-19-31)26-41-37(47)33-25-32(45)27-44(33)38(48)36(39(2,3)4)43-34(46)15-9-7-12-22-50-24-14-8-13-23-49-21-11-6-5-10-20-40/h16-19,28,32-33,36,45H,5-15,20-27H2,1-4H3,(H,41,47)(H,43,46)/t32-,33+,36-/m1/s1
Canonical SMILES
CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)CCCCCOCCCCCOCCCCCCCl)O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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