t-Boc-N-amido-PEG5-acid - CAS 1347750-78-0

t-Boc-N-amido-PEG5-acid is a cleavable (5-unit PEG) ADC linker, as well as a PEG- and alkyl/ether-based PROTAC linker that can be used to synthesize antibody-drug conjugates (ADCs) or PROTACs.

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Molecular Formula
C18H35NO9
Molecular Weight
409.47

t-Boc-N-amido-PEG5-acid

    • Specification
      • Related CAS
        187848-68-6 (polymer)
        Purity
        ≥95%
        Solubility
        Soluble in DMSO
        Appearance
        Pale Yellow Oily Liquid
        Storage
        Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        3-[2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
        Synonyms
        Boc-NH-PEG5-CH2CH2COOH; t-Boc-NH-amido-PEG5-COOH; Boc-NH-PEG5-COOH; t-boc-N-amido-PEG5-propionic acid; 2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azatricosan-23-oic acid; 5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid, 1-(1,1-dimethylethyl) ester; 3,8,11,14,17,20-Hexaoxa-5-azatricosan-23-oic acid, 2,2-dimethyl-4-oxo-
    • Properties
      • Boiling Point
        536.9±50.0°C (Predicted)
        Density
        1.123±0.06 g/cm3 (Predicted)
        InChI Key
        RVYBVZICXVYKRD-UHFFFAOYSA-N
        InChI
        InChI=1S/C18H35NO9/c1-18(2,3)28-17(22)19-5-7-24-9-11-26-13-15-27-14-12-25-10-8-23-6-4-16(20)21/h4-15H2,1-3H3,(H,19,22)(H,20,21)
        Canonical SMILES
        CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCC(=O)O
Bio Calculators
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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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