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TCO-PEG4-NHS ester - CAS 1613439-69-2

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Molecular Formula
C24H38N2O10
Molecular Weight
514.57

TCO-PEG4-NHS ester

    • Specification
      • Purity
        >99.5%
        Solubility
        10 mm in DMSO
        Appearance
        Solid
        Shelf Life
        0-4℃ for short term (days to weeks), or -20℃ for long term (months).
        Storage
        -20°C
        Shipping
        -20°C (International: -20°C)
        Synonyms
        TCO PEG4 succinimidyl ester; 2,5-dioxopyrrolidin-1-yl (E)-1-(cyclooct-4-en-1-yloxy)-1-oxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
    • Properties
      • Density
        1.2±0.1 g/cm3
        InChI Key
        ZKPMRASGLDBKPF-OWOJBTEDSA-N
        InChI
        InChI=1S/C24H38N2O10/c27-21-8-9-22(28)26(21)36-23(29)10-12-31-14-16-33-18-19-34-17-15-32-13-11-25-24(30)35-20-6-4-2-1-3-5-7-20/h1-2,20H,3-19H2,(H,25,30)/b2-1+
        Canonical SMILES
        C1CC=CCCC(C1)OC(=O)NCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
        Biological Activity
        TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]
    • Preparing Stock Solutions
      • ConcentrationVolumeMass1 mg5 mg10 mg
        1 mM1.9434 mL9.7169 mL19.4337 mL
        5 mM0.3887 mL1.9434 mL3.8867 mL
        10 mM0.1943 mL0.9717 mL1.9434 mL
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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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